Inesa Paliulytė was born in 1957. She is a graduate of Juozas Miltinis Theatre Studio, located in Panevėžys. The actress also graduated from the Lunacharsky State Institute of Theatre Arts (GITIS, currently the Russian Academy of Theatre Arts) in Moscow. Since 1979 Paliulytė has been an actress at the National Kaunas Drama Theatre (NKDT). She is one of the founders and teachers of a theatre school under NKDT called My Theatre (Lith. Mano teatras).