N. Lepeškaitė was born in 1947, studied acting at the Lithuanian State Conservatoire (currently the Lithuanian Academy of Music and Theatre). Since 1968 she has been performing at the National Kaunas Drama Theatre. N. Lepeškaitė is a popular actress in Lithuanian cinema and has performed roles in Latvian and Estonian cinemas. She founded the My Theatre (Lith. Mano teatras) theatre school. The actress is also a director and a teacher.